Assessment of electrical dyssynchrony using 12-lead ECG: A comparative analysis of proposed metrics
DOI:
https://doi.org/10.14311/CTJ.2026.56.02Abstract
Cardiac resynchronization therapy (CRT) represents a well-established therapeutic strategy widely implemented in the treatment of patients with heart failure. By addressing electrical dyssynchrony, CRT improves mechanical cardiac function and reduces the risk of heart failure-related hospitalization. Current guidelines suggest QRS duration and left bundle branch block morphology for assessing electrical dyssynchrony. However, 30% of CRT patients do not respond to the therapy. This paper reviews the alternative metrics of electrical dyssynchrony derived from standard 12-lead ECG for patient selection and/or pacing programming in CRT. Specifically, a detailed analysis of recently proposed parameters of electrical dyssynchrony to elucidate whether they offer advantages over the currently used criteria was performed.
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Tamerlan Yusifov, Anastasia Sedova, Ph.D.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of the first publication with the work simultaneously licensed under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) that allows others to share the work with an acknowledgment of the work's authorship and initial publication in CTJ.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website or ResearchGate) prior to and during the submission process, as it can lead to productive exchanges.
CTJ requires that all of the content of the manuscript has been created by its respective authors or that permission to use a copyrighted material has been obtained by the authors before submitting the manuscript to CTJ. CTJ requires that authors have not used any copyrighted material illegally, as for example a picture from another journal or book, a photo, etc. It is the author’s responsibility to use only materials not violating the copyright law. When in doubt, CTJ may ask the authors to supply the pertinent permission or agreement about the use of a copyrighted material.
The opinions expressed in CTJ articles are those of authors and do not necessarily reflect the views of the publishers or the Czech Society for Biomedical Engineering and Medical Informatics.
