DESIGN CONCEPTS FOR PREVENTING GAS BUBBLE INTERFERENCE IN MICROFLUIDIC DEVICES

Sebastian Richert, Oliver Peters, Vu Hoa Nguyen, Uwe Schnakenberg

Abstract


Unintendedly introduced gas bubbles in channels can significantly interfere with performance and behavior of microfluidic systems. Thus, there is a high demand for smart microfluidic system designs which are capable of preventing gas bubbles. In this work, we develop two different bubble interference preventing system designs:
a degasser device that actively removes gas bubbles from the liquid based on pressure driven gas permeation, and a passive micro channel design that provides a guiding mechanism based on the gas bubbles’ effort to minimize their surface energy. The effective performances of the devices are demonstrated.


Keywords


microfluidics; gas bubble removal; degassing

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This work is licensed under a Creative Commons Attribution 4.0 International License.

ISSN 0301-5491 (Print)
ISSN 2336-5552 (Online)
Published by the Czech Society for Biomedical Engineering and Medical Informatics and the Faculty of Biomedical Engineering, Czech Technical University in Prague.