ANALÝZA POVRCHU MAGNETICKÝCH MIKROČÁSTIC PROSTŘEDNICTVÍM MIKROSKOPIE ATOMÁRNÍCH SIL

Hana Zapletalová, Klára Pížová, Jakub Malohlava, Milan Vůjtek, Hana Kolářová

Abstract


ANALYSIS OF MAGNETIC MICRO PARTICLES SURFACE USING THE ATOMICFORCE MICROSCOPY. Although the magnetic nano and micro particles are studied since seventies, they have gained significant attention in biochemical and medicine applications in last ten years. The main benefit of use magnetic particles lies in spatial manipulation through external magnetic field and selective surface modifciation of large surface area. Our study is focused on microscopic analysis of four magnetic carriers used for DNA isolation visualised by atomic force microscopy and optical microscopy. Based on our results was approved rough and porous particle surface and determined the particle size distribution. The AFM imaging of DNA adsorbed on rough surface of magnetic carrieris discussed.

Keywords


magnetic porous glass particles; atomic force microscopy; magnetic microspheres

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ISSN 0301-5491 (Print)
ISSN 2336-5552 (Online)
Published by the Czech Society for Biomedical Engineering and Medical Informatics and the Faculty of Biomedical Engineering, Czech Technical University in Prague.