DEPENDENCE OF THE VISCOSITY COEFFICIENT OF THE NIOSOMAL DISPERSION ON THE TEMPERATURE AND PARTICLE SIZE OF THE DISPERSED PHASE

Elena Igorevna Diskaeva; Olga Vladimirovna Vecher; Igor Alexandrovich Bazikov; Karine Sergeevna Elbekyan; Elena Nikolaevna Diskaeva

doi:10.14311/AP.2021.61.0336

Authors

Elena Igorevna Diskaeva Stavropol State Medical University, Department of Physics and Mathematics, Mira 310, 355017 Stavropol, Russia
Olga Vladimirovna Vecher Stavropol State Medical University, Department of Physics and Mathematics, Mira 310, 355017 Stavropol, Russia https://orcid.org/0000-0002-6743-874X
Igor Alexandrovich Bazikov Stavropol State Medical University, Department of Microbiology, Mira 310, 355017 Stavropol, Russia https://orcid.org/0000-0001-9207-6552
Karine Sergeevna Elbekyan Stavropol State Medical University, Department of General and Biological Chemistry, Mira 310, 355017 Stavropol, Russia https://orcid.org/0000-0003-2403-8663
Elena Nikolaevna Diskaeva Branch of the Federal State Budget Educational Institution of Higher Education “MIREA – Russian Technological University” in Stavropol, Department of Industrial Technology, Kulakov Avenue 8, 355035 Stavropol, Russia https://orcid.org/0000-0002-5185-6023

DOI:

https://doi.org/10.14311/AP.2021.61.0336

Keywords:

Niosome, nonionic surfactant vesicles, viscosity of niosomal dispersion, vesical size.

Abstract

The aim of this study was to experimentally investigate the dependence of viscosity coefficient of niosomal dispersion based on PEG-12 Dimethicone on the temperature and size of niosomes vesicles. The experiments were carried out with niosomes, the average size of which varied from 85 to 125 nm. The temperature varied from 20 to 60 °C, the volume concentration varied from 1 to 10 %. The particle size was determined by scanning electron microscopy (SEM) with subsequent statistical data processing. This study showed that the viscosity of niosomal dispersions significantly depends on both the temperature and the size of niosomes vesicles. With increasing temperature, the viscosity of niosomal dispersions decreases and with increasing particle size, the viscosity increases.

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